Creation of MedInsights Unleashed
Zahra Ramji and John Collins initially crossed paths while employed at a global pharmaceutical company specializing in cutting-edge therapies for challenging cancers. Together, they embarked on extensive global travels, engaging with oncology specialists to ensure widespread awareness of these innovative treatments. Recognizing a pressing need to streamline access to information about emerging therapies, they conceived the idea for the MedInsights Unleashed podcast. MedInsights Unleashed features a diverse group of specialists, including researchers, practising physicians and patient advocates
Recent Insights
In this latest episode of MedInsights Unleashed, we are delighted to welcome Dr. Paulo Hoff, MD, PhD, Professor of Clinical Oncology at the Department of Radiology and Oncology, University of SĂŁo Paulo. Dr. Hoff discusses the rising incidence of colorectal cancer in younger populations, highlighting key risk factors including poor diet, sedentary lifestyle, and obesity. He emphasizes the critical importance of beginning regular screening at age 45.
The discussion covers the complete treatment journey, from initial diagnosis through staging—which determines both local and distant tumor spread—to help create optimal treatment plans. Dr. Hoff explains that some patients may require temporary or permanent colostomy procedures.
A significant focus is placed on the emerging total neoadjuvant treatment (TNT) approach, which administers all chemotherapy and radiation before surgery to improve outcomes. The episode concludes by emphasizing the value of collaborative care, bringing together different oncology specialists for comprehensive treatment